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Document ID ca-cdwgtdc-2018-03-23 Title Copper in drinking water: Guideline technical document for consultation URL https://www.canada.ca/en/health-canada/programs/consultation-copper-drinking-water/document.html Jurisdiction /ca Subdomain(s) Drinking water, Water quality standards, Treatment methods, Monitoring and analysis Language en Status completed Analyzed at 2026-03-17 13:12:55.869283+00:00 Relevance Proposed Health Canada guideline for copper in drinking water (MAC and AO).

Q Qualitative Requirements (37)

Req ID Category Intent Legal Status Name Subdomain(s) Context Conditions Confidence
#Q001operationaltreatmentrecommendedCorrosion Control Practice Targetdrinking waterNevertheless, corrosion control practices should target the MAC and not the elimination of aesthetic concerns as this could jeopardize other water quality priorities such as lead control.When implementing corrosion control practices.high
#Q002monitoringoperationalguidanceAesthetic Objective Localised Investigationdrinking waterUtilities may choose to use the AO to trigger a site-specific or localised water quality/corrosion investigation.When addressing aesthetic objective (AO) exceedances or aesthetic concerns.high
#Q003monitoringoperationalrecommendedAnalytical Sample Preparation for Particulate Copperdrinking waterThese methods should include sample preparation to ensure that they are able to detect both dissolved and particulate copper.When performing analytical methods to measure total copper in drinking water.high
#Q004administrativereportingrecommendedGuidance on Implementationdrinking waterSpecific guidance related to the implementation of drinking water guidelines should be obtained from the appropriate drinking water authority in the affected jurisdiction.When seeking specific guidance related to the implementation of drinking water guidelines.high
#Q005treatmenthealthrecommendedCorrosion Control within Distribution and Plumbing Systemsdrinking waterConsidering that copper levels at the consumer's tap may be significantly higher than levels at the treatment plant or in the distribution system, strategies to reduce exposure to copper will need to focus on controlling corrosion within the distribution and plumbing systems.When implementing strategies to reduce exposure to copper.high
#Q006monitoringhealthrecommendedFocus of Copper Monitoringdrinking waterCopper monitoring should focus on areas known or likely to have new copper piping and where water quality conditions are potentially corrosive (e.g., low pH, dead ends, low or high alkalinity waters) and in consecutive systems.When conducting copper monitoring.high
#Q007corrective_actionhealthrecommendedExceedance Investigation and Corrective Actionsdrinking waterAn exceedance of the proposed MAC should be investigated and followed by the appropriate corrective actions to reduce the copper levels below the MAC.In the event of an exceedance of the proposed MAC.high
#Q008corrective_actionoperationalrecommendedCorrective Action Cause Assessmentdrinking waterHowever, these actions should be based on an assessment of the cause of the exceedance using appropriate protocols, such as those found in Guidance on Controlling Corrosion in Drinking Water Distribution Systems.When taking actions to investigate and reduce copper level exceedances.high
#Q009monitoringreportingrecommendedCompliance Monitoring Focus Areasdrinking waterCompliance monitoring should be conducted at the consumer's tap and focus on areas known or likely to have new copper pipe installations and should include areas or zones (geographical areas within which the quality of drinking water is considered approximately uniform) supplied by potentially corrosive water (e.g., low pH, low or high alkalinity).When conducting compliance monitoring for typical community exposure.high
#Q010monitoringhealthrecommendedPriority Sites for Samplingdrinking waterSpecifically, priority should be given to sites known to have new copper plumbing or when the water supply has a pH < 7, with or without disinfection or oxidation processes and alkalinity < 25 mg CaCO3/L, or pH >7 and alkalinity >200 mg CaCO3/L with disinfection or oxidation processes, regardless of the age of copper.When selecting priority sites for monitoring.high
#Q011monitoringoperationalrecommendedMonitoring Requirements for Orthophosphate Treatment Systemsdrinking waterA water system using orthophosphate treatment for corrosion control having a PO4 residual less than 3.3 mg PO4/L, should also monitor for copper.When a water system uses orthophosphate treatment for corrosion control and has a PO4 residual less than 3.3 mg PO4/L.high
#Q012monitoringhealthrecommendedMonitoring at Daycare Facilitiesdrinking waterDaycare facilities should also be prioritized for monitoring to ensure that the most sensitive population (i.e., infants) is captured.When prioritizing locations for compliance sampling.high
#Q013monitoringreportingrecommendedSampling Frequency and Scaledrinking waterSampling should be conducted at least once per year, with the number of sites to be monitored determined based on the size of the drinking water system and the type of building.Routine sampling unless reduced by regulator or non-corrosive conditions.high
#Q014monitoringoperationalrecommendedAnalytical Method Selection and Interferencesdrinking waterIn selecting an analytical method, consideration should be given to the water matrix to minimize the effect of interfering agents by using the prescribed sample pre-treatment or mitigation steps can help eliminate or decrease the effects of interfering agents.When selecting and utilizing analytical methods for copper testing.high
#Q015monitoringoperationalrecommendedParticulate Copper Dispersion and Sample Preservationdrinking waterAs such, the current protocol may underestimate total copper in drinking water when particulate copper is present and best practice for the preservation step should be considered.When preserving samples potentially containing particulate copper.high
#Q016monitoringoperationalrecommendedNitric Acid Addition Precautionsdrinking waterIt is important to note that the addition of 2% nitric acid should be undertaken by qualified personnel and using appropriate precautions.When adding 2% nitric acid to water samples for preservation.high
#Q017monitoringhealthrecommendedHomeowner Sampling Acidification Restrictionsdrinking waterTo this end, if sampling is conducted by homeowners, the sample should only be acidified and held upon arrival at the laboratory.When sampling is conducted by homeowners.high
#Q018operationaltreatmentrecommendedPilot-Scale Studies for Water Quality Changesdrinking waterUtilities should undertake pilot-scale or pipe rig studies to understand how water quality changes to control copper will affect various chemical constituents in the treated water (e.g., iron and manganese) as well as materials in the distribution system (e.g., scale stability, lead-bearing components).When planning to adjust water quality to control copper.high
#Q019designoperationalrecommendedWater Age Considerations for Green Buildingsdrinking waterAs green building technology becomes more prevalent, consideration should be made for the implications of increased water age on water quality and corrosion.When designing or operating water systems in green buildings.medium
#Q020operationaltreatmentrecommendedPilot-Scale Studies Before Water Quality Changesdrinking waterBefore changing water quality to achieve a new treatment goal, such as corrosion control, utilities should undertake pilot-scale studies to understand how a proposed water quality amendment will affect various components of their distribution system.Before changing water quality to achieve a new treatment goal.high
#Q021operationaltreatmentrecommendedTest Pipe-Rigs for Mitigation Strategydrinking waterThe use of test pipe-rigs under site specific water quality conditions is recommended, as the testing process can be helpful in selecting an effective corrosion control strategy and aid in anticipating unintended impacts.When selecting a mitigation strategy for copper.high
#Q022operationalhealthrecommendedSystem Flushing Practicesdrinking waterPeriodic flushing throughout the day and extensive flushing following long stagnation periods (vacation periods, weekends) may therefore be advisable to provide suitable water quality throughout the day.Following long stagnation periods.high
#Q023treatmenthealthrecommendedCorrosion Inhibitor Additives Certificationdrinking waterHealth Canada recommends that water utilities choose drinking water additives, such as corrosion inhibitors, that have been certified as conforming to the applicable NSF/ANSI health-based standard.When selecting drinking water additives like corrosion inhibitors.high
#Q024operationaltreatmentrecommendedUse of Copper Pitting Mitigation Toolsdrinking waterutilities should consider using the tools such as those found in Sarver et al. (2011).To avoid or mitigate copper pitting and address key water quality changes.high
#Q025operationaltreatmentrecommendedPilot-Testing for Copper Pitting Diagnosesdrinking waterIn addition, utilities should conduct pilot-testing to evaluate their particular water quality and any proposed or potential changes to water quality to both diagnose a problem and to identify workable solutions (Lytle and Schock, 2008; Lytle et al., 2012).When diagnosing copper pitting problems or identifying solutions.high
#Q026operationaloperationalrecommendedDezincification Resistance Communication and Encouragementdrinking waterSarver et al. (2011) suggested that utilities determine the aggressiveness of their particular water quality towards brass alloys and communicate this information to stakeholders (consumers and developers), and encourage the use of dezincification resistant brass alloys.To address potential brass dezincification.high
#Q027monitoringtreatmentrecommendedWater Testing Prior to Treatment Device Installationdrinking waterBefore a treatment device is installed, the water should be tested to determine general water chemistry and to verify the concentration of copper.Before installing a residential drinking water treatment device.high
#Q028monitoringtreatmentrecommendedPeriodic Efficacy Testing of Treatment Devicesdrinking waterPeriodic testing by an accredited laboratory should be conducted on both the water entering the treatment device and the finished water to verify that the treatment device is effective.When evaluating the performance of residential treatment devices.high
#Q029operationaltreatmentrecommendedAdsorption Media Longevity Verification and Device Servicingdrinking waterConsumers should verify the expected longevity of the adsorption media in their treatment device as per the manufacturer’s recommendations and service the device when required.When using point-of-use or point-of-entry treatment devices utilizing adsorption.high
#Q030treatmenthealthrecommendedResidential Treatment Device Certification Recommendationdrinking waterHealth Canada strongly recommends that consumers use devices that have been certified by an accredited certification body as meeting the appropriate NSF/ANSI drinking water treatment unit standard(s).When selecting residential drinking water treatment devices.high
#Q031designhealthrecommendedTreatment System Components Material Certificationdrinking waterHealth Canada strongly recommends that any components used in these treatment systems be certified to NSF/ANSI Standard 61- Drinking Water System Components Health Effects (NSF/ANSI, 2016a) and NSF/ANSI Standard 372 – Drinking Water Systems Components Lead Content (NSF/ANSI, 2016b).For any components used in residential water treatment systems.high
#Q032treatmenthealthrecommendedMitigation Strategy Corroson Control Focusdrinking waterstrategies for reducing exposure to copper from drinking water should focus on corrosion control through approaches such as water quality adjustments and the use of corrosion inhibitors.When implementing strategies to reduce exposure to copper.high
#Q033monitoringoperationalrecommendedSampling Best Practices for Total Metalsdrinking waterBest practice leading to a better estimation of total metals include ensuring that no aliquot or volume transfers occur prior to preservation or analysis, in situ sample preservation where feasible, maintaining a minimum holding time of 16 hours after preservation, thoroughly mixing the sample prior to analysis and taking the aliquot directly from the original sample bottleWhen performing sampling to estimate total metals in drinking water.high
#Q034treatmentoperationalrecommendedMitigation Strategy Multi-Metal Considerationdrinking waterThe selection of a mitigation strategy for copper should take into consideration other metals present since different strategies, including water quality adjustments, may impact various metals differently.When selecting a mitigation strategy for copper.high
#Q035treatmentoperationalmandatoryReverse Osmosis Product Water pH Adjustmentdrinking waterSince reverse osmosis (RO) continually and completely removes alkalinity in water, it will continually lower the pH of treated water and increase its corrosivity. Therefore, the product water pH must be adjusted to avoid corrosion issues in the distribution system such as the leaching of lead and copperWhen using reverse osmosis (RO) treatment processes.high
#Q036monitoringoperationalmandatoryCorrosion Inhibitor Residual Monitoringdrinking waterMeasuring the concentration of inhibitors within the distribution system is part of good corrosion control practice.For utilities using corrosion inhibitors in the distribution system.high
#Q037prohibitionoperationalrecommendedRestriction on Sequestering Agents for Copper Mitigationdrinking waterGenerally, the use of sequestering agents is not recommended for mitigating copper release.When attempting to mitigate copper release in the distribution or plumbing system.high

P Quantitative Requirements (58)

Req ID Category Intent Legal Status Name Subdomain(s) Limit Type Limit Value Context Conditions Confidence
#P001chemicalhealthguidelineTotal copper maximum acceptable concentrationdrinking waterMAC2 mg/LProposed guideline for total copper in drinking water, based on a sample of water taken at the tap.Based on a sample of water taken at the tap.high
#P002chemicalaestheticguidelineTotal copper aesthetic objectivedrinking waterAO1 mg/LProposed aesthetic objective for total copper in drinking water.high
#P003physicaloperationalrecommendedLow pH monitoring triggerdrinking waterrequirement< 7 pHPriority should be given to monitoring sites when the water supply has a low pH.With or without disinfection or oxidation processes and alkalinity < 25 mg CaCO3/L.high
#P004chemicaloperationalrecommendedLow alkalinity monitoring triggerdrinking waterrequirement< 25 mg CaCO3/LPriority should be given to monitoring sites when the water supply has low alkalinity.When pH < 7, with or without disinfection or oxidation processes.high
#P005physicaloperationalrecommendedHigh pH monitoring triggerdrinking waterrequirement> 7 pHPriority should be given to monitoring sites when the water supply has high pH coupled with high alkalinity.Alkalinity > 200 mg CaCO3/L with disinfection or oxidation processes.high
#P006chemicaloperationalrecommendedHigh alkalinity monitoring triggerdrinking waterrequirement> 200 mg CaCO3/LPriority should be given to monitoring sites when the water supply has high alkalinity coupled with high pH.pH > 7 with disinfection or oxidation processes.high
#P007chemicaloperationalrecommendedPO4 residual monitoring triggerdrinking waterrequirement< 3.3 mg PO4/LA water system using orthophosphate treatment for corrosion control having a low PO4 residual should also monitor for copper.When using orthophosphate treatment for corrosion control.high
#P008chemicaltreatmentmandatoryInfluent copper concentration for treatment device certificationdrinking waterrequirement3 mg/LTo be certified to NSF/ANSI Standard 53 for the removal of copper, the device must be capable of reducing this influent concentration.Applies to certification of drinking water treatment units under NSF/ANSI Standard 53.high
#P009chemicaltreatmentmandatoryFinal (effluent) copper concentration for treatment device certificationdrinking waterrequirement< 1.3 mg/LTo be certified to NSF/ANSI Standard 53, 58, or 62 for the removal of copper, the device must achieve this maximum final effluent concentration.From an influent concentration of 3 mg/L.high
#P010operationalreportingrecommendedMinimum monitoring frequencydrinking waterrequirement1 per yearSampling frequency for copper monitoring at the tap.Number of sites determined based on size of the system and type of building.high
#P011designoperationalguidancePractical quantitation limit (PQL) for copperdrinking waterrequirement0.05 mg/LCurrent practical quantitation limit (PQL) for copper as indicated by U.S. EPA.high
#P012physicaltreatmentmandatoryTurbidity threshold for hot digestiondrinking waterrequirement> 1 NTUThreshold for adding hydrochloric acid for hot digestion during sample preparation.When sample turbidity is above 1 NTU.high
#P013operationalreportingmandatorySample preservation holding timedrinking waterrequirement16 hoursRequired holding time after acid preservation before analysis.Standard acid preservation using 0.15% nitric acid.high
#P014operationaltreatmentguidanceHeat-shock temperature for blue water mitigationdrinking watertreatment_goal> 60 °CShort term management strategy for blue water events.Used to mitigate microbiologically induced corrosion.high
#P015chemicalhealthguidelineTolerable daily intake (TDI) for copperdrinking waterrequirement426 µg/kg bw per dayThe point of departure identified as the tolerable daily intake used for MAC derivation.Based on GI effects and liver function in formula-fed infants.high
#P016chemicalhealthmandatoryQuebec copper drinking water standarddrinking waterrequirement1.0 mg/LNorme québécoise pour le cuivre dans l’eau potable.Applicable for distribution systems in Quebec.high
#P017chemicalhealthguidelineRecommended Daily Allowance (RDA) for Adultsdrinking waterrequirement900 µg/dayRecommended daily allowance established for adults.Applies to adults (19–70+ year-old) of both genders.high
#P018chemicalhealthguidelineTolerable Upper Intake Level (UL) for Adultsdrinking waterrequirement10000 µg/dayTolerable upper intake level for copper in adults.Based on absence of liver or GI effects.high
#P019chemicalhealthguidelineInfant average body weight for MAC calculationdrinking waterrequirement7 kgAverage body weight of an infant used in the calculation of the proposed MAC.Infant age group 0–6 months.high
#P020chemicalhealthguidelineInfant daily volume of tap water consumptiondrinking waterrequirement0.75 L/dayEstimated daily volume of tap water consumed by a bottle-fed infant used in the MAC calculation.Infant age group 0–6 months.high
#P021chemicalhealthguidelineDrinking water allocation factordrinking waterrequirement0.5 unitlessSource contribution factor allocated to drinking water for the MAC calculation.Based on formula representing the total diet in non-breast fed infants.high
#P022physicalaestheticguidanceCopper taste threshold rangedrinking waterrequirement0.4–0.8 mg/LReported taste threshold values for copper in water.high
#P023physicalaestheticguidanceVisual detection threshold in bathtubdrinking waterrequirement0.3 mg/LConcentration at which copper becomes visible in a white bathtub.Typical observation distance of approximately 460 mm (18 inches).high
#P024chemicalhealthguidelineWHO copper drinking water guidelinedrinking waterMAC2 mg/LProvisional health-based guideline value set by the World Health Organization.Based on a provisional maximum tolerable daily intake of 0.5 mg/kg.high
#P025chemicaltreatmentmandatoryUS EPA copper action leveldrinking waterrequirement1.3 mg/LAction level established under the US EPA Lead and Copper Rule.Applies to the 90th percentile of samples taken at customer taps.high
#P026chemicalhealthguidanceCalifornia EPA copper public health goaldrinking watertreatment_goal0.3 mg/LNon-regulatory public health goal developed by California EPA.Based on infants as a sensitive population.high
#P027chemicalhealthguidelineAustralian health-based copper limitdrinking waterMAC2 mg/LLevel set in Australian Drinking Water Guidelines to prevent health issues.high
#P028chemicalaestheticguidelineAustralian aesthetic copper limitdrinking waterAO1 mg/LLevel set in Australian Drinking Water Guidelines to prevent taste and staining.high
#P029operationaloperationalmandatoryStandard nitric acid preservation concentrationdrinking waterrequirement0.15 %Standard acid preservation concentration for total copper in water samples.Requires a pH < 2.high
#P030operationaloperationalrecommendedHigh-recovery nitric acid preservation concentrationdrinking waterrequirement2 %Increased acid strength recommended for better recovery of particulate copper.Should be undertaken by qualified personnel with appropriate precautions.high
#P031chemicalhealthguidelineRecommended Daily Allowance (RDA) for Childrendrinking waterrequirement340–890 µg/dayThe U.S. National Academy of Medicine has established recommended daily allowances for children.Applies to children aged 1 to 18 years.high
#P032chemicalhealthguidelineTolerable Upper Intake Levels (UL) for Childrendrinking waterrequirement1000–8000 µg/dayTolerable upper intake levels for children to prevent adverse health effects.Applies to children aged 1 to 18 years.high
#P033chemicalhealthguidelineTolerable Upper Intake Levels (UL) for Pregnant and Lactating Womendrinking waterrequirement8000–10000 µg/dayUL established for pregnant and lactating women.high
#P034chemicalhealthguidelineAdequate Intake (AI) for infants (0–6 months)drinking waterrequirement200 µg/dayAdequate intake based on copper levels in human milk.Infants 0-6 months of age.high
#P035chemicalhealthguidelineAdequate Intake (AI) for infants (7–12 months)drinking waterrequirement220 µg/dayAdequate intake for older infants.Infants 7-12 months of age.high
#P036chemicalhealthguidelineWHO/FAO formula copper minimumdrinking waterrequirement35 µg/100 kcalRecommended minimum for infant formula marketed to comply with normal nutritional requirements.Liquid or powder infant formula.high
#P037chemicalhealthmandatoryUS EPA Maximum Contaminant Level Goal/Maximum Contaminant Leveldrinking waterMAC1.3 mg/LUS EPA health-based limit goal and level for copper in drinking water.Based on adverse gastrointestinal tract effects following acute exposure.high
#P038chemicalaestheticguidanceUS EPA Secondary Maximum Contaminant Level (SMCL)drinking waterAO1 mg/LSecondary limit established by US EPA based on aesthetic considerations.Based on taste and blue/green staining.high
#P039designreportingguidanceAnalytical method detection limits (MDL) rangedrinking waterrequirement0.02–500 µg/LThe method detection limits for the approved U.S. EPA methods for measuring copper.Dependent on sample matrix, instrumentation, and operating conditions.high
#P040designreportingmandatorySM 3111B instrument detection limitdrinking waterrequirement0.01 mg/LInstrument detection limit for flame atomic absorption spectrometry method.high
#P041designreportingmandatorySM 3113B estimated detection leveldrinking waterrequirement0.7 µg/LEstimated detection level for electrothermal atomic absorption spectrometry.Optimum concentration range of 5–100 µg/L.high
#P042designreportingmandatoryEPA 200.7 Rev 4.4 MDLdrinking waterrequirement0.003 mg/LMethod detection limit for ICP-AES method.high
#P043designreportingmandatoryEPA 200.5 Rev 4.2 MDLdrinking waterrequirement0.3 µg/LMethod detection limit for axially viewed ICP-AES method.Calculated reporting limit of 0.7 µg/L.high
#P044designreportingmandatoryEPA 200.8 Rev 5.4 MDL (Scanning)drinking waterrequirement0.5 µg/LMethod detection limit for ICP-MS in scanning mode.Standard ICP-MS protocol.high
#P045designreportingmandatoryHach 10272 MDLdrinking waterrequirement0.06 mg/LMethod detection limit for colorimetric Bicinchoninate Method.high
#P046physicalaestheticguidanceBroad copper taste threshold rangedrinking waterrequirement0.0035 to > 5 mg/LWide range of reported taste thresholds in various scientific studies.Variability due to sensory test methods and water types used.high
#P047physicalaestheticguidanceMaximum copper concentration for visible particulate in glassdrinking waterrequirement3 mg/LThreshold for copper particulate to be noticeable to an observer looking at a glass of water.Standard observation of drinking glass.high
#P048operationaltreatmentguidanceOrthophosphate dosage for high alkalinity waterdrinking watertreatment_goal3 mg/LOrthophosphate dosage found sufficient to decrease copper release in high alkalinity water.Alkalinity 273 CaCO3 mg/L, pH 7.4.high
#P049chemicalhealthguidelineWHO PMTDI for copperdrinking waterrequirement0.5 mg/kgProvisional maximum tolerable daily intake proposed by JECFA and used by WHO for the 1993 guideline.Based on liver toxicity observed in dog studies.high
#P050chemicalhealthguidelineWHO drinking water allocation factor (1993)drinking waterrequirement0.1 unitlessAllocation factor used by WHO in 1993 to set the provisional health-based guideline value.10% of the PMTDI allocated to drinking water.high
#P051operationaltreatmentguidanceInitial sodium silicate dose (Schock)drinking watertreatment_goal25–30 mg/LInitial dose of sodium silicate used in a medium-sized utility to solve iron and leaching issues.Increased pH from 6.3 to 7.5.high
#P052operationaltreatmentguidanceIncreased sodium silicate dose (Schock)drinking watertreatment_goal45–55 mg/LIncreased sodium silicate dose to achieve greater reductions in metal levels.Increased pH to 7.5.high
#P053operationaltreatmentguidanceSodium silicate dose (Lintereur - Low)drinking watertreatment_goal3 mg/LLow dose tested in sodium silicate comparison study.high
#P054operationaltreatmentguidanceSodium silicate dose (Lintereur - Mid)drinking watertreatment_goal6 mg/LMiddle dose tested in sodium silicate comparison study.high
#P055operationaltreatmentguidanceSodium silicate dose (Lintereur - High)drinking watertreatment_goal12 mg/LHigh dose tested in sodium silicate comparison study showing lowest copper release.high
#P056operationaltreatmentguidanceSodium silicate treatment (Woszczynski)drinking watertreatment_goal18 mg-Si/LTreatment dosage used in comparison study against phosphate.pH 7.3 and pH 6.3.high
#P057operationaltreatmentguidancePhosphate treatment (Woszczynski)drinking watertreatment_goal0.8 mg-PO4/LTreatment dosage used in comparison study against silicate.pH 7.3.high
#P058chemicalhealthguidelineTypical human milk copper leveldrinking waterrequirement200–250 µg/LCopper levels in human milk used as a basis for infant adequate intakes.high

D Definitions (80)

Req ID Category Name Context Confidence
#D001RDAthe average daily intake level sufficient to meet the nutrient requirements of 97.5% of the apparently healthy population of a given sex and agehigh
#D002Alkalinitya measure of the capacity of the water to neutralize acids and serves to control the buffer intensity of most water systemsmedium
#D003ADAlzheimer’s diseasehigh
#D004ANSIAmerican National Standards Institutehigh
#D005AOaesthetic objectivehigh
#D006BMDbenchmark dosehigh
#D007BMDL0595% lower confidence limit on the benchmark dose for a 5% change in effecthigh
#D008BMDL1095% lower confidence limit on the benchmark dose for a 10% change in effecthigh
#D009bwbody weighthigh
#D010CASChemical Abstracts Servicehigh
#D011Cpcaeruloplasminhigh
#D012Cucopperhigh
#D013CSMRchloride to sulphate mass ratiohigh
#D014Cu(I)cuprous ionhigh
#D015Cu(II)cupric ionhigh
#D016DICdissolved inorganic carbonatehigh
#D017DNAdeoxyribonucleic acidhigh
#D018DOdissolved oxygenhigh
#D019EPAEnvironmental Protection Agency (U.S.)high
#D020EPSexopolymeric substanceshigh
#D021GACgranular activated carbonhigh
#D022GGTgamma glutamyl transferasehigh
#D023GIgastrointestinalhigh
#D024GMgeometric meanhigh
#D025GOTglutamic-oxaloacetic aminotransferasehigh
#D026ICTidiopathic copper toxicosishigh
#D027IUDsintrauterine deviceshigh
#D028LOAELlowest observed adverse effect levelhigh
#D029MACmaximum acceptable concentrationhigh
#D030MTmetallothioneinhigh
#D031MDLmethod detection limithigh
#D032MICmicrobiologically influenced corrosionhigh
#D033MKDMenkes’ diseasehigh
#D034NOAELno observed adverse effect levelhigh
#D035NOMnatural organic matterhigh
#D036NPCNational Plumbing Code of Canadahigh
#D037NSFNSF Internationalhigh
#D038NTUnephelometric turbidity unithigh
#D039OHSoccipital horn syndromehigh
#D040ORPredox potentialhigh
#D041PEXcross-linked polyethylenehigh
#D042POUpoint of use (device)high
#D043PQLpractical quantitation limithigh
#D044RDA (Acronym)recommended daily allowancehigh
#D045ROreverse osmosishigh
#D046SDstandard deviationhigh
#D047SODsuperoxide dismutasehigh
#D048TBARSthiobarbituric acid reactive substanceshigh
#D049TDStotal diet studyhigh
#D050TICTyrolean infantile cirrhosishigh
#D051WDWilson’s diseasehigh
#D052WHOWorld Health Organizationhigh
#D053zonesgeographical areas within which the quality of drinking water is considered approximately uniformhigh
#D054total copperreferring to all of the major oxidation stateshigh
#D055copperreferring to both Cu(I) and Cu(II), which cycle from one to the other, are soluble, bioavailable, and considered the most relevant from a toxicological standpointhigh
#D056free copperloosely bound to albumin and low-molecular weight moleculeshigh
#D057Microbiologically influenced corrosion (MIC)results from a reaction between the pipe material and organisms, their metabolic by-products, or bothhigh
#D058Wilson’s disease (WD)an hepatolenticular degenerationhigh
#D059LD50Oral lethal doseshigh
#D060ULstolerable upper intake levelshigh
#D061TDItolerable daily intakehigh
#D062Brassesalloys of copper and zinc, with other minor constituents, such as leadhigh
#D0635-hydroxytryptamine-4 receptorsreceptor subtypes that respond to serotoninhigh
#D064PMTDIprovisional maximum tolerable daily intakehigh
#D065MCLGmaximum contaminant level goalhigh
#D066MCLmaximum contaminant levelhigh
#D067SMCLsecondary Maximum Contaminant Levelhigh
#D068Institute of Medicine (IOM)The U.S. National Academy of Medicine (formerly called the Institute of Medicine)high
#D069dissolved inorganic carbon (DIC)Alkalinity is generally used interchangeably with dissolved inorganic carbon (DIC).high
#D070Pitting corrosiona form of non-uniform corrosion in all types of copper pipe and tubing and can ultimately lead to pinhole leakshigh
#D071ATPase7Bthe transporter affected in Wilson’s diseasehigh
#D072ATP7Athe transporter affected by Menkes diseasehigh
#D073Cpa ferroxidase synthesized and bound to copper within the liver, for the delivery of the nutrient to peripheral tissueshigh
#D074ICP-AESinductively coupled plasma atomic emission spectroscopyhigh
#D075ICP-MSinductively coupled plasma mass spectroscopyhigh
#D076SCCStandards Council of Canadahigh
#D077ROSreactive oxygen specieshigh
#D078DICdissolved inorganic carbonhigh
#D079Cu(III)trivalent copper ionhigh
#D080OH•hydroxyl radicalhigh